Planning

Monday, May 6, 2013

Time Event  
11:00 - 12:00 Welcome - Registration and poster mounting  
12:00 - 14:00 Lunch buffet  
14:00 - 14:10 Welcome session - Prof. Bruno Ségui - M. Sébastien Guibert - INSERM UMR 1037, Cancer Research Center of Toulouse, France  
14:10 - 15:00 Introducing lecture - Linear ubiquitination in cell death and inflammation - Prof. Henning Walczak - University College London, United Kingdom  
15:00 - 17:30 Apoptotic signalling and resistance - Chairpersons: Dr. Catherine Pellat-Deceunynck (Nantes, France), Dr. Patrick Legembre (Rennes, France), Dr. Olivier Micheau (Dijon, France)  
15:00 - 15:20 › Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia - Lingli Yuan, INSERM UMR 1037, Centre de recherches en cancérologie de Toulouse, France  
15:20 - 15:40 › Vitamin D3 and lenalidomide synergize to induce apoptosis in mantle cell lymphoma via unmethylation of BIK - Carole Brosseau, Institut de Recherche en Santé de l'Université de Nantes, France  
15:40 - 16:00 › Caloric restriction modulates Mcl-1 expression and sensitizes lymphomas to BH3 mimetic in vivo - Ophélie MEYNET, INSERM U1065, Centre Méditerranéen de Médecine Moléculaire, Nice, France  
16:30 - 16:50 › Trim17, a novel E3 ubiquitin-ligase for the anti-apoptotic protein Mcl-1 - Solange DESAGHER, Institut de génétique moléculaire de Montpellier, France  
16:50 - 17:10 › Therapeutic interest to target the Phosphoinositide-3-Kinase (PI3K) – mTOR (Target Of Rapamycin) pathway in pancreatic Cancer-Associated Fibroblasts - Camille Duluc, INSERM UMR 1037, Centre de Recherches en Cancérologie de Toulouse, France  
17:10 - 17:30 › Chemosensitization of pancreatic cancer cells using gene transfer: from the proof of concept to phase I clinical trial - Pierre Cordelier, INSERM U1037, Centre de Recherches en Cancérologie de Toulouse, France  
17:30 - 20:00 poster - session 1  
20:30 - 23:00 Dinner  

Tuesday, May 7, 2013

Time Event  
08:45 - 09:15 Seminar - The mechanism to overcome the chemoresistance of leukemia cells through autophagic cell death - Prof. Toshiro Okazaki - Kanazawa Medical University, Uchinada, Ishikawa, Japan  
09:15 - 10:35 Cell death alternative signalling and resistance - Chairpersons: Dr. Eric Chevet (Bordeaux, France), Dr. Jean-Ehrland Ricci (Nice, France), Dr. Philippe Juin (Nantes, France)  
09:15 - 09:35 › Impact of select IRE1alpha somatic mutations in oncogenesis. - Stéphanie Lhomond, Université Bordeaux Segalen, Bordeaux, France  
09:35 - 09:55 › The hypoxia-inducible GAPDH activates HIF-1 and promotes aggressiveness of c-Myc-driven B-lymphoma. - Johanna CHICHE, INSERM U1065, Centre Méditerranéen de Médecine Moléculaire, Nice, France  
09:55 - 10:15 › Cleaved CD95L promotes cell migration in breast cancers by inducing an EGFR-driven signal. - Marine Malleter, Inserm U1085, IRSET, Rennes, France  
10:15 - 10:35 › Ionizing radiations sustain Glioblastoma cell plasticity to a stem-like phenotype : a new pathway of radioresistance? - Anthony LEMARIE, INSERM UMR 1037, Centre de recherches en cancérologie de Toulouse, France  
10:35 - 10:55 Coffee break  
10:55 - 11:30 Seminar - Pivotal role of sphingolipids on the stimulation of autophagy-mediated cancer cell death by cannabinoids - Dr. Guillermo Velasco - Complutense University, Spain  
11:30 - 12:30 poster - session 2  
12:30 - 14:00 Lunch  
14:00 - 16:00 Cell death and immune response - Chairpersons: Dr. Frédéric Rieux-Laucat (Paris, France), Dr. Nicolas Bidère (Paris, France)  
14:00 - 14:30 › Caspase-8, cell death mechanisms, autoimmunity and cancer - Razqallah Hakem, University Health Network, Toronto University, Canada  
14:30 - 14:50 › LUBAC participates to antigen receptor-mediated NF-κB activation and survival of lymphoma cells - Sonia Dubois, INSERM U1014, Paris, France  
14:50 - 15:10 › Somatic RAS Mutations : From Auto-Immunity To Leukemia - Frédéric Rieux-Laucat, INSERM U768, Paris, France  
15:10 - 15:30 › Role of Tumor Necrosis Factor-alpha on CD8-dependent immune responses during melanoma progression - Bertrand florie, INSERM UMR 1037, Centre de Recherches en Cancérologie de Toulouse, France  
15:30 - 16:00 Human T cell immunological synapses in health and disease - Dr. Salvatore Valitutti - INSERM U1043, Toulouse, France  
16:00 - 16:30 Coffee break  
16:30 - 17:15 Closing lecture - Non apoptotic cell death in a model organism - Dr. Pierre Golstein - Marseille-Luminy Immunology Center, Marseille, France  
17:15 - 17:30 Conclusion - End of congress  
  
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